F3922
Sigma
Anti-Fibroblast Growth Factor Receptor-3, Extracellular antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
| Synonym: | Anti-FGFR-3 |
| MDL number: | MFCD01633348 |
Description
| Immunogen | synthetic peptide corresponding to amino acids 359-372 of the extracellular region of human fibroblast growth factor receptor-3. |
| Preparation Note | Affinity isolated on a peptide-agarose column. |
| Physical form | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide. |
Properties
| antibody form | affinity isolated antibody |
| clone | (polyclonal) |
| form | buffered aqueous solution |
| mol wt | antigen mol wt ~120 kDa |
| species reactivity | human |
| application(s) | immunoblotting: 1:500 using extract of FGFR-3 transfected cells |
| immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using protease-digested, human and animal tissue sections | |
| Gene Information | human ... FGFR3(2261) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | NWG |
References
| reference | Jing, X., et al., Fibroblast growth factor 23 reduces expression of type IIa Na+/Pi co-transporter by signaling through a receptor functionally distinct from the known FGFRs in opossum kidney cells. Genes Cells 10, 489-502, (2005) Abstract |
